For the second straight year, the Ducks' promising season ends with a humiliating CFP loss, this time with Dante Moore throwing a pick-six on the very first play.

No. 1 seed Indiana is emerging from the College Football Playoff semifinals looking like one of the most dominant teams of the modern era and a potentially inevitable national champion. However, No. 10 seed Miami will have something to say about it on Jan. 19 inside Hard Rock Stadium, when the teams collide with a national championship on the line.

Friday’s semifinal is a Big Ten affair, but the pairing is far from traditional as the Ducks and Hoosiers both seek a first national title.

Oregon got off to a rough start to Friday's semifinal game when Dante Moore threw a pick-six on the first play from scrimmage. Moore responded by leading the Ducks on a game-tying touchdown drive, although he struggled with ball control later in the half.

From the first play from scrimmage, Oregon was overmatched and outplayed in Friday night's College Football Playoff semifinal loss to Indiana in Atlanta. The Ducks turned it over on three of their first six possessions, each of those mistakes leading to touchdowns for the Hoosiers and a further increasing deficit that culminated in a 56-22 defeat.

Oregon Ducks running back Noah Whittington is expected to play in the College Football Playoff game vs. Indiana, but there is a catch.