Hepatosplenomegaly refers to swelling and enlargement of the liver and spleen, in the upper abdomen. It can result from an infection, an injury, some types of anemia, and various other health factors.

A condition that makes your liver and spleen swell, HPM has many causes and may cause symptoms that include pain, fatigue, nausea and vomiting among many others. Hepatosplenomegaly (HPM) is a disorder ...