A deadly crash on U.S. Highway 301 in Thonotosassa shut down a portion of the roadway Friday night, causing major traffic delays in the area.

A Hillsborough County Sheriff's Office deputy is dead after a crash with a semi-truck on U.S. Highway 301 in Thononotassa.

A person was struck and killed in what appeared to be a one-car accident at the intersection of U.S. Highway 301 and S.C. Highway 4 late Tuesday night.

A truck carrying about a million bees on U.S. Highway 301 crashed into a tractor-trailer on Tuesday morning, releasing thousands of the insects all over the freeway, according to local news ...

Section of Highway 301 re-opens after train derails in Marion County The API failed to deliver the resource. A CSX train derailed early Saturday, shutting down part of Highway 301 in the Pee Dee.

One person is dead after driving off US Highway 301 in Orangeburg County, SC and hit utility pole, the South Carolina Highway Patrol said.

Two of the four people killed in a wrong-way crash in Wilson County have been identified. The North Carolina Highway Patrol said Greta Lynette Pender-Ray, 53, and Brandi Jyasia Sherrod, 21 were ...

A man from Rocky Mount is accused of assaulting a teenage driver during a road rage incident on Highway 301 in Wilson.