During interphase, the cell's DNA is not condensed and is loosely distributed. A stain for heterochromatin (which indicates the position of chromosomes) shows this broad distribution of chromatin in a ...
The Anaphase Promoting Complex/Cyclosome (APC/C), a large ubiquitin ligase, targets key cell-cycle regulators such as cyclin A2 (the major A-type cyclin in human somatic cells) and cyclin B1 for ...
KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.