USC vs Iowa prediction and betting odds | Nov. 15, 2025
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Iowa Football: Hawkeyes Underdogs in Trip to USC
Iowa’s last trip to the Coliseum to face USC came way back in 1976. The Hawkeyes were drubbed 55-0 in that one. Iowa is 3-7 all-time vs USC and 2-6 in regular season matchups. Both of those regular season wins came on the road in LA (1950 and 1961).
The Iowa Hawkeyes knew one of their games still needed to air on the Big Ten Network as part of their streaming contract. It was safe to assume that Iowa vs. th
The Trojans have been in the top 25 all season long, and mvoed to No. 17 after a win over Northwestern last Friday.
USC leads 7-3, but Iowa did win the most recent game — a 49-24 blowout in the 2019 Holiday Bowl. Ihmir Smith-Marsette had a historic game, scoring three times in three different ways. Smith-Marsette scored a rushing touchdown, a receiving touchdown and a kickoff return touchdown, all in the second quarter.
Iowa (6-3) at No. 20 USC (7-2), Nov. 15 at 3:30 p.m. EST. USC ranks 5th in FBS in third down percentage, converting 51.9% of the time. USC ranks 67th in the FBS averaging 54.2 penalty yards per game, compared to Iowa's 1st-ranked 20.2 per-game average.
Iowa football 's Nov. 15 game at USC now has a TV assignment. The Hawkeyes ' 2:30 p.m. CT game against the Trojans will be televised by Big Ten Network. The Big Ten Conference matchup had previously been designated as "CBS or Big Ten Network." It was announced Sunday that Iowa vs. USC will be shown on BTN.
Oregon game had the kind of flavor the Hawkeyes wanted, but the Ducks won anyway. That is scary for USC, but the Trojans may have one edge: