In patients who are at risk of developing ulcer complications and whose arthritis cannot be relieved by simple analgesics, combination therapy with NSAIDs and a gastroprotective agent has ...

Sucampo reported top-line results from its Phase 2 trial of orally administered cobiprostone for the prevention of gastric ulcers and other gastrointestinal injuries in patients treated with ...

Indomethacin has been proved by epidemiological and experimental studies to be closely associated with peptic ulcer development. Vardenafil is a potent phosphodiesterase 5 inhibitor and its effects on ...

Stress-induced gastric ulcer is one of the common complications affecting patients after trauma, mainly leading to gastrointestinal bleeding and perforation, and severe cases may be life-threatening.

Despite the availability of potent gastroprotective agents and gastric-sparing NSAIDs, hospitalization due to NSAID-related gastrointestinal complications remains an important problem, particularly ...