The APC/C (anaphase-promoting complex; also known as the cyclosome) is an E3 ubiquitin ligase that mediates the ubiquitylation of key substrates for their degradation by the proteasome at precise ...
In the process of replicating themselves, cells have another choice: do they want to make an identical copy and be left with two cells? Or do they want to make four “half-copies”, in preparation for ...
The anaphase-promoting complex/cyclosome (APC/C) is an ubiquitin ligase that functions during mitosis. Here we identify the transcriptional regulator, transcriptional intermediary factor 1γ, TIF1γ, as ...
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