Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...
PURPOSE: To identify the role of p53 pathway alteration(s) as predictors of treatment outcome in patients with advanced, resectable, squamous cell carcinoma (SCC) of the larynx and pharynx treated ...
Cancer arises when your cells grow uncontrollably and refuse to die when they should. Normally, your body is equipped with regulatory processes to prevent this chaos. One such mechanism involves a ...
AZD1775 plays a role in the regulation of ferroptosis by dually targeting the cystine uptake and the WEE1-SETDB1 axis, while the activation of the p53-SLC7A11 cascade by Act. D augments ...
This article and associated images are based on a poster originally authored by Sarona Jacob Anderson and presented at ELRIG Drug Discovery 2025 in affiliation with University of Salford. This poster ...
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