Expert Rev Ophthalmol. 2013;8(6):527-537. Vascular endothelial cells form the inner lining of blood vessels; overlying them are pericytes, branched cells within the basement membranes of capillaries ...

Mice bearing the PDGF-Rα-GFP construct were described (13). Production of green-fluorescent protein (GFP) is controlled by the endogenous pdgf-rα promoter. GFP expression in PDGF-Rα-GFP mice spatially ...

Platelet-derived growth factors (PDGFs) are mitogenic during early development, promoting the proliferation of undifferentiated mesenchymal cells and specific progenitor populations. At later ...

Platelet-derived growth factor (PDGF) signaling is essential for processes involving cell motility and differentiation during embryonic development in a wide variety of organisms including the mouse, ...

In research that one day may lead to the discovery of how to regenerate tissue damaged by heart disease, researchers have identified PDGF as a key factor in the proliferation and transformation of ...

Introduction. Platelet‑derived growth factor (PDGF) and P‑selectin, the low‑molecular weight proteins located mainly in the platelet α-granules, are considered to be biologically active markers of ...

Adocia said it will halt development of its diabetic foot ulcer candidate BioChaperone (BC) PDGF following its failure in a Phase III trial, joining several companies that have met with clinical ...

Scientists from Tokyo Metropolitan University have discovered that a protein called platelet-derived growth factor subunit B (PDGF-B) is continuously secreted from skeletal muscle cells and helps to ...

Ophthotech has seen its share price decimated after it announced over the weekend that its big hope, and what much of its financing has been centered around in recent years, failed to help wet AMD ...

Expert Rev Ophthalmol. 2013;8(6):527-537. Protein kinase C-mediated contraction of RPE cells is stopped by an anti-PDGF antibody. Unfortunately, blocking PDGF is ineffective at suppressing PVR in most ...