Post-translational modifications are critical to the functioning of cellular subsystems, and are therefore of great biological interest. Modifications can be detected from tandem mass spectra by ...

The direct molecular weight determination and structural analysis of polypeptides and peptide mixtures have become amenable by the recent development of fast atom bombardment (FABMS) and 252 Cf-plasma ...

Peptide mapping is a critical quality test to confirm the primary structure of proteins used in biotherapeutics such as monoclonal antibodies and antibody-drug conjugates. It relies on protein ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

Peptide mapping for biotherapeutic proteins relies on protein digestion which includes the enzymatic treatment of a protein to produce peptide fragments to further characterize specific peptide ...