This paper revisits the problem of power analysis and sample size calculations in randomised experiments.
Our motivation here is to calculate the power of 3 statistical tests used when there are genetic traits that operate under a pleiotropic mode of inheritance and when qualitative phenotypes are defined ...
Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
An advantage of the supremum log-rank over the standard log-rank statistic is an increased sensitivity to a wider variety of stochastic ordering alternatives. In this article, we develop a formula for ...
Individual prediction uncertainty is a key aspect of clinical prediction model performance; however, standard performance metrics do not capture it. Consequently, a model might offer sufficient ...
Phase III, Randomized Study of the Effects of Parenteral Iron, Oral Iron, or No Iron Supplementation on the Erythropoietic Response to Darbepoetin Alfa for Patients With Chemotherapy-Associated Anemia ...
The probability that the null hypothesis will be rejected when it is actually true is called the false positive rate and is determined by the significance level of the test (called alpha which is ...