Mucosal-associated invariant T (MAIT) cell count was associated with risk of hospitalization in patients with chronic obstructive pulmonary disease (COPD) independent of forced expiratory volume ...

Prolonged exposure to cigarette smoke destroys the air sacs in mouse lungs (left). But this destruction is prevented in mice lacking MAIT cells (right). Cigarette smoking is widespread and deadly, yet ...

It was once thought that inflammation and immune responses in the brain were limited; that is was a so-called immune privileged organ. But there is increasing evidence to the contrary. New research ...

Rutgers researchers deactivated the gene that produces mucosal-associated invariant T cells (MAITs) in mice and compared the cognitive function of normal and MAIT cell-deficient mice. Initially, the ...

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of ...

Mice altered to prevent the production of a particular type of immune cell struggled to form new memories. Could the underproduction of poorly understood immune cells contribute to Alzheimer's disease ...

Biomunex's ambition is to develop the next generation of immunotherapies in oncology: MAIT engagers, bispecific antibodies capable of identifying, mobilizing, and activating MAIT cells, a ...

Ipsen secures exclusive global rights to develop, manufacture and commercialize BMX-502, a pre-clinical novel T cell engager (TCE) with first-in-class potential BMX-502 is a bispecific antibody ...

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine (TCM)—using single-cell RNA sequencing (scRNA-seq) of ...

Ipsen has gambled up to $610 million on a new class of bispecific T-cell engagers. The biobuck bet has landed the French drugmaker exclusive global rights to a preclinical Biomunex Pharmaceuticals ...