The discovery of ArcS, which can utilize a nucleoside as a minimum substrate, provides new insights into the synthesis of precursor molecules for these modified nucleosides. The results of this ...
Analysis of Factors That Correlate With Mucositis in Recipients of Autologous and Allogeneic Stem-Cell Transplants PURPOSE: The nucleoside analogs fludarabine, 2′-deoxycoformycin (DCF), and ...
Pathogen recognition is based on the presence of Toll-like receptors (TLRs), which detect pathogen-associated molecular patterns (PAMPs) to coordinate the immune cascade. These receptors are encoded ...
Acute lymphoblastic leukemia is the most common type of childhood leukemia, with about 5,000 children diagnosed in the U.S. each year. Now researchers have synthesized a nonnatural deoxynucleoside ...
The circular dichroism data on 17 adenine nucleosides show that the 260- and 207-mμ absorption systems of the adenine chromophore each contain at least two electronic transitions. The CD maxima are ...
Contamination of Strain L cell cultures by pleuropneumonia-like organisms (PPLO) resulted in a complete inhibition of the incorporation of tritiated thymidine and uridine. Contaminated cultures were ...
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