Key points A 39-year-old otherwise healthy man presented to the emergency department with severe rectal pain and a 3-day history of constipation. He had presented to another community emergency ...
Despite advancements in treatment and HIV viral suppression, people with HIV experience a risk of myocardial infarction that is 1.73 times higher than in people without HIV.[1][1] Believed to be in ...
Not always, but too often, my patient and I both watch my right hand as it shakes. Sometimes, to finish writing a prescription, I steady it with my left hand. Oops. And I wonder: Should I address the ...
Multiple sclerosis (MS) often begins in early adulthood, and symptoms may include fatigue, pain, and mood changes. These may not be outwardly visible but can be deeply disabling.[1][1] Clinicians ...
Most antihistamines are safe during pregnancy and breastfeeding Systematic reviews of observational studies show no association with adverse fetal or maternal outcomes with antihistamine use during ...
A 68-year-old man presented to the gastroenterology clinic with recurrent melena over 3 months with a history of recurrent spontaneous epistaxis and a familial pattern of similar bleeding among his ...
Opinion
Mitigating the global impact of changing HIV policies in the US: a call for advocacy and action
Key points On Jan. 20, 2025, the incoming United States administration froze all foreign assistance funds for 90 days, including the President’s Emergency Plan for AIDS Relief (PEPFAR) funding.[1][1] ...
A 57-year-old woman was admitted to hospital with a 2-month history of fever and rash that had begun on her right hand and spread across her body over the previous 10 days. She had palp–able purpura ...
Background: Determining optimal timing for intensifying the frequency of physician encounters for type 2 diabetes mellitus (T2DM) requires trade-offs between timely care and clinician burden. We aimed ...
Delirium occurs in 30%–50% of adults aged 65 years or older admitted to hospital, and may be hypoactive (lethargy, reduced psychomotor functioning), hyperactive (agitation, hallucinations) or mixed.1 ...
More than 85 000 (2.3 per 1000) people in Canada have cerebral palsy, a group of disorders resulting from a nonprogressive brain lesion early in life. Seventy-five percent of those living with ...
Cardiovascular risk thresholds for intensifying primary care encounter frequency for patients with type 2 diabetes mellitus: a target trial emulation ...
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