Atom-swapping blueprint could streamline synthesis of pharmaceutical building blocks

Researchers from NUS have pioneered a photocatalytic atom-swapping transformation that converts oxetanes into a variety of four-membered saturated cyclic molecules, which are key scaffolds in ...

Bristol-Myers Squibb, Takeda, Astex Join AI Consortium to Train OpenFold3 for Accelerated Drug Discovery

Bristol-Myers Squibb Company (NYSE:BMY) is one of the most undervalued stocks to buy and hold for 5 years. On October 1, ...
The Conversation

Mysterious molecule found on brown dwarf casts further doubt on potential signs of life on Venus

Brown dwarfs: too small to be stars, too big to be planets. Only discovered in the 1990s, these in-between cosmic objects aren’t big enough to burn as hot and bright as a true star, instead usually ...
Frontiers

Establishment of a bleeding risk model for low-molecular-weight heparin in cancer-associated venous thromboembolism: a single-center retrospective study

1 Department of Pharmacy, Chengdu Fifth People’s Hospital, Chengdu, Sichuan, China 2 Department of Emergency Medicine, Chengdu Fifth People’s Hospital, Chengdu, Sichuan, China Objectives: To establish ...
C&EN

Defective Host Immunity in a Mouse Hindlimb Ischemia Model Attenuates the Blood Flow Recovery Promoted by an mRNA/LNP Formulation

mRNA therapeutics represent a relatively new therapeutic modality with the potential for a diverse range of clinical applications, from vaccines to regenerative therapy. Recent clinical advances in ...
IEEE

Research on Molecular Property Prediction Model Base on Random Forest and LSTM Network

Abstract: In today's scientific research, the application of advanced technologies such as machine learning, deep learning and Bayesian optimization is increasingly widespread. They are integrated ...
Business Wire

Variational AI Announces Oversubscribed $5.5 Million Financing to Launch Foundation Model for Small Molecule Drug Discovery

VANCOUVER, British Columbia--(BUSINESS WIRE)--Variational AI, the company behind Enki™, an advanced foundation model for small molecule drug discovery, today ...
C&EN

Kinetics of Polymorphic Phase Transformations of o-Aminobenzoic Acid: Application of a Dispersive Kinetic Model Plus Molecular Dynamics Simulation of Prenucleation Aggregates

Materials Science, Schrödinger, Inc., 1540 Broadway, 24th Floor, New York, New York 10036, United States Therapeutics Group, Schrödinger, Inc., 1540 Broadway, 24th ...