Both hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are characterized by thrombotic microangiopathy (TMA), affecting mainly the kidney and brain, respectively. Diagnosis ...

For all primary TMA syndromes, the vascular pathological abnormalities that are observed in routine specimens are the same, as illustrated in the center of the figure by the renal arteriole occlusion ...

We monitored the levels of various cytokines and chemokines, as well as an adhesion molecule and factors related to vascular endothelial damage, in three patients with thrombotic thrombocytopenic ...

Thrombotic thrombocytopenic purpura (TTP) is a rare disorder that affects your blood’s tendency to clot. In this disease, tiny clots form throughout your body. These tiny clots have major consequences ...

Understanding of the pathophysiology of thrombotic microangiopathies — a group of rare yet life-threatening hematologic conditions — has evolved in recent years along with better access to diagnostic ...

X. Long Zheng, MD, PhD, gives an overview on acquired thrombotic thrombocytopenic purpura including prevalence and the typical patient presentation. X. Long Zheng, MD, PhD: What is acquired TTP? TTP ...

An organism provisionally classified as a microtatobiote, order of rickettsiales, family of bartonellaceae, was isolated from two patients with hemolytic-uremic syndrome (HUS) and from another with ...

Thrombotic microangiopathy due to thrombotic thrombocytopenia should be suspected in a patient with otherwise unexplained thrombocytopenia and anemia, even without fever, renal dysfunction or ...

Pseudo-thrombotic microangiopathy (pseudo-TMA) is relatively easy to treat, but it is also easy to mistake for a much more serious condition, thrombotic thrombocytopenic purpura (TTP). In a new report ...

The hallmark of both post-CABG HITT and post-CABG TTP is unexplained thrombocytopenia and an evidence of thrombotic complications. HITT is usually present with either venous or arterial thrombosis, or ...

Plasma exchange is the essential treatment for TTP, but it has no known benefit for patients with cancer-induced or drug-induced TMA. We will describe cancer-induced and drug-induced TMA using the ...